Harvard breakthrough in folding prediction?

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Stephen

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Message 31097 - Posted: 14 Nov 2006, 0:37:53 UTC

Here is a link to an article about discussing a new folding technique. It claims to be able to model folding for 10 microseconds, at least "at least a thousand times longer than previous methods":

http://www.physorg.com/news82056528.html

I'm not a biochemist, so I'd be curious to get feedback on how much of a breakthrough this is, and how it relates to the work done with Rosetta@home.

Stephen
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Message 31133 - Posted: 14 Nov 2006, 16:23:46 UTC

Vijay Pande's response from F@H is here:
http://forum.folding-community.org/ftopic16807.html
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ronalds8
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Message 31173 - Posted: 15 Nov 2006, 6:51:48 UTC

should be a great achievement, although im not a specialist either.
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David Baker
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Message 31281 - Posted: 17 Nov 2006, 3:51:16 UTC

I gave a seminar at Harvard today, and had a chance to talk with my friend Eugene Shakhnovich, the senior author on the paper discussed in this thread. I haven't read or even seen the paper myself, but he told me he was embarrassed about all the media attention which he said was way overblown. Universities have press offices which can hype up papers much more than the scientists feel they deserve, and often considerable accuracy is lost in the process (I don't know in this case as I haven't read the paper or the press release, but I have certainly seen this in the past).
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David Baker
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Message 32442 - Posted: 11 Dec 2006, 6:00:18 UTC

The Harvard group entered in CASP, which is great--you can view their results on the CASP7 web page (the group name is shakskol-abinitio). you can see the press release was a bit off.
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Message boards : Rosetta@home Science : Harvard breakthrough in folding prediction?



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